Did you know?
20% of our bone tissues are replaced with the set of new bone tissues annually, through the bone remodeling process.
Have you ever thought how our skeletal increases and shapes itself according to our age? How it grows in size and how it maintains itself? All these questions can be answered by understanding the process of bone remodeling.
Bone remodeling is a continuous and lifelong process of bone metabolism. It occurs on multiple sites simultaneously, and in this way, about 20% of our bone tissues get replaced annually.
So, basically bone remolding is a process in which an old bone is replaced by a new bone. Remodeling plays a very important role in the development of bones. It also helps in maintaining the calcium level in the body and in repairing micro injuries.
The Process of Bone Remodeling
Bone remodeling consists of two major processes: Resorption (breaking or disintegration of the old bone) and ossification (formation of the new bone). Three types of cells play a very important role in the process:
Osteoclasts are multinucleated cells. They are responsible for bone resorption. They travel to the sites of old bones or the bones which need to be repaired. They secrete acid phosphatase which disintegrate the bone
Osteoblasts are mononucleated cells. They help in the formation of the new bone. They secrete alkaline phosphate, which helps in the deposition of calcium and phosphate, resulting in the formation of a new bone.
Those osteoblasts which are not present on the surface of the bone are called osteocytes. They are found in the lacunae between the lamellae in a bone. These cells help in maintaining oxygen and mineral level in the bone.
After understanding the functioning of the cells that participate in the bone remodeling, let us discuss the bone remodeling process in detail. Though remodeling consists of two major processes, it can be divided into five steps.
These cells interact with the receptors which triggers pre-osteoclasts fusions and form multinucleotide osteoclasts. The osteoclasts gather on one site and form a small pit which is known as Howship's lacunae.
Once the bone is dissolved to the required extend, osteoclast undergo apoptosis or self-destruction. This is done to avoid excess resorption.
All the cells which help to conduct the process are regulated by hormones. Any imbalance in the production of hormones can directly lead to the imbalance in the resorption and formation process. This may affect the body mass and bone health.
Bone remodeling in one of the most important functions of our body, which helps in maintaining skeletal health and even maintains calcium levels in the body. So, take care of yourself to help this process function properly.